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Spheroid and organoid can be used as a model of SARS‐Cov‐2 infection (A, B) to understand the mechanism of virus entry into cells (C, D). (E) An efficient drug candidate should eliminate the virus while maintaining cell viability inside spheroids. Toxic drug candidates show no antiviral effect or even toxic effects in both cells and virus [Color figure can be viewed at wileyonlinelibrary.com]
