Table 2. Performance assessment of the classification model using the CV procedure.

Dataset	10-fold CV	C-index	Brier score	Log-rank P-value (geo.mean)
Training	3-omics training (60%)	0.73 ± 0.06	0.14 ± 0.01	1.40e−4
	RNA only	0.67 ± 0.07	0.15 ± 0.01	1.93e−3
	miRNA only	0.65 ± 0.05	0.14 ± 0.01	5.84e−4
	Methylation only	0.68 ± 0.09	0.15 ± 0.02	1.07e−3
Test	3-omics test (40%)	0.64 ± 0.11	0.16 ± 0.02	2.92e−2
	RNA only	0.63 ± 0.16	0.16 ± 0.02	4.07e−2
	miRNA only	0.62 ± 0.12	0.17 ± 0.02	3.96e−2
	Methylation only	0.60 ± 0.14	0.18 ± 0.02	4.72e−2

CV, cross-validation