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. 2020 Nov 4;24(23):13589–13599. doi: 10.1111/jcmm.15222

Figure 6.

Figure 6

The mechanism of miR‐214 in the regulation of brain injury with the involvement of Mfn2/Pkm2 interaction. General anaesthesia promotes the expression of miR‐214, while the down‐regulation of miR‐214 up‐regulates the Mfn2 expression to promote the interaction between Pkm2 and Mfn2, thereby facilitating the mitochondrial fusion in rats following general anaesthesia