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. 2020 Nov 14;24(24):14247–14256. doi: 10.1111/jcmm.16041

FIGURE 7.

FIGURE 7

Cask gene promoter hypermethylation in IL‐1β–treated INS‐1 cell. Bisulphite sequencing analysis for indicated CpG islands in Cask promoter region comparing INS‐1 cells from 1 ng/mL IL‐1β for 48 h treatment and control group (representative result shown here). Each horizontal line with dots is an independent result, and a representative is shown here. Filled black circles represent methylated CpG sites, whereas open circles represent unmethylated CpG sites