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. 2020 Dec 19;6(12):e05734. doi: 10.1016/j.heliyon.2020.e05734

Figure 7.

Figure 7

Model for miR-1911-3p function on mEAK-7-mediated mTOR signaling. miR-1911-3p is synthesized and binds to the 3′-UTR of MEAK7 through the RISC complex. This binding down-regulates MEAK7 translation and subsequently suppresses mTOR signaling in cells, resulting in a substantial decrease in cell proliferation and migration.