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. 2020 Dec 14;15:3323–3334. doi: 10.2147/COPD.S274354

Table 2.

Correlation Analysis Between Inflammatory Markers and Pulmonary Function Parameters

PLR NLR CRP
r P r P r P
FVC (absolute) −0.149 0.015 −0.105 0.080 −0.069 0.388
FVC (%predicted) −0.192 0.002 −0.262 <0.001 −0.236 0.003
FEV1 (absolute) 0.101 0.098 −0.203 <0.001 −0.156 0.049
FEV1 (% predicted) −0.094 0.126 −0.217 <0.001 −0.288 <0.001
FEV1/FVC 0.101 0.098 0.045 0.460 −0.048 0.545
DLCO (absolute) −0.271 <0.001 −0.235 <0.001 −0.112 0.179
DLCO (% predicted) −0.139 0.032 −0.152 0.016 −0.205 0.013
PLR 0.718 <0.001 0.187 0.022
NLR 0.718 <0.001 0.427 <0.001
CRP 0.187 0.022 0.427 <0.001

Note: P-value calculated using Spearman’s rho.

Abbreviations: CRP, c-reactive protein; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; DLCO, diffusing capacity of the lung for carbon monoxide; NLR, neutrophil–lymphocyte ratio; PLR, platelet–lymphocyte ratio.