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. 2020 Dec 3;44:101131. doi: 10.1016/j.molmet.2020.101131

Figure 1.

Figure 1

LKB1 in glucose metabolic reprogramming. LKB1 controls glucose metabolism by inducing the expression of several genes that encode the enzymes of glycolysis, aerobic oxidation, the pentose phosphate pathway, and gluconeogenesis. Abbreviations: hexokinase II (HK II), phosphofructokinase 1 (PFK1), aldolase (ALDO), glyceraldehyde 3-phosphatedehydrogenase (GAPDH), phosphoglycerate kinase (PGK), α-enolase (ENO1), pyruvate kinase (PK), glucose (Glc), glucose-6-phosphate (G-6-P), fructose-6-phosphate (F-6-P), fructose-1,6-bisphosphate (FBP), glyceraldehyde-3-phosphate (GAP), 1,3-diphosphoglycerate (1,3-P2G), 3-phosphoglycerate (3-PG), phosphoenolpyruvate (PEP), 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKBP3), fructose 2,6-bisphosphate (F-2,6-BP).