Cu levels in serum are higher in obese patients and positively correlate with BMI. (A) Serum Cu levels in female and male obese patients and lean controls (Ctrl). (B) Serum Cu concentration plotted against BMI values for both obese and lean patients. (C) Serum Cu levels are plotted against BMI values only for obese individuals. (Pearson’s r and p values were calculated by using a linear regression analysis. Student’s t-test, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05. The data are presented as mean ± SEM.)