Table 2.
No | Compounds | Formula | Related category | RT (min) | Mass (m/z) | GseL VS Control | GseH VS Control | Anti VS Control | |||
---|---|---|---|---|---|---|---|---|---|---|---|
Trend | P value | Trend | P value | Trend | P value | ||||||
1 | probucol | C31 H48 O2 S2 | lipid modifying agents | 7.30 | 533.3401 | up2 | 0.000 | up | 0.000 | up | 0.000 |
2 | all-trans-18- hydroxyretinoic acid |
C20 H28 O3 | prenol lipids | 9.95 | 316.2031 | up | 0.000 | up | 0.001 | up | 0.000 |
3 | arachidonoyl dopamine | C28 H41 N O3 | lipids | 10.67 | 439.3139 | up | 0.000 | up | 0.000 | up | 0.000 |
4 | sphinganine | C18 H39 N O2 | sphingolipid | 12.47 | 301.2975 | up | 0.000 | up | 0.000 | up | 0.000 |
5 | k-strophanthoside | C42 H64 O19 | sterol lipids | 16.52 | 872.3828 | down | 0.000 | down3 | 0.000 | / | 0.873 |
6 | oxamate | C2 H3 N O3 | oxamic acid | 2.21 | 106.0363 | up | 0.003 | /5 | 0.930 | up4 | 0.032 |
7 | cinnamic acid | C9 H8 O2 | phenylalanine | 4.56 | 148.0519 | down | 0.016 | / | 0.631 | / | 0.829 |
8 | L-2-Methyltryptophan | C12 H14 N2 O2 | amino acid | 5.42 | 218.1071 | down | 0.000 | down | 0.000 | down | 0.022 |
9 | ornaline | C10 H18 N2 O6 | nopalinic acid | 14.08 | 279.1419 | up | 0.000 | up | 0.047 | up | 0.020 |
10 | pepstatin | C34 H63 N5 O9 | aspartate protease | 21.27 | 702.49 | down | 0.003 | down | 0.004 | / | 0.064 |
11 | GDP-D-mannuronate | C16 H23 N5 O17 P2 | amino sugar and nucleotide sugar | 13.15 | 636.0884 | up | 0.000 | up | 0.010 | / | 0.896 |
12 | UDP-4-keto-rhamnose | C15 H22 N2 O16 P2 | amino sugar and nucleotide sugar | 14.43 | 548.0458 | down | 0.001 | down | 0.000 | / | 0.433 |
13 | Ala Ile Pro | C14 H25 N3 O4 | peptides | 1.23 | 299.1859 | up | 0.000 | up | 0.001 | / | 0.919 |
14 | Gly Leu Thr | C12 H23 N3 O5 | peptides | 4.88 | 306.1934 | down | 0.002 | down | 0.001 | / | 0.775 |
15 | Phe Met Lys | C20 H32 N4 O4 S | peptides | 7.66 | 424.2147 | down | 0.000 | down | 0.020 | / | 0.405 |
16 | Met Met Val | C15 H29 N3 O4 | peptides | 10.29 | 401.1434 | up | 0.000 | up | 0.000 | / | 0.898 |
17 | acetyltropine | C10 H17 N O2 | tropane alkaloids | 13.44 | 183.1255 | up | 0.000 | / | 0.122 | up | 0.000 |
18 | belladonnine | C34 H42 N2 O4 | tropane alkaloids | 14.36 | 542.3187 | up | 0.000 | up | 0.001 | / | 0.898 |
19 | salannin | C34 H44 O9 | triterpenoids | 16.42 | 618.2865 | up | 0.012 | / | 0.121 | / | 0.064 |
20 | (+)-prosopinine | C18 H35 N O3 | piperidine alkaloids | 18.18 | 313.2615 | down | 0.000 | down | 0.000 | down | 0.000 |
21 | phenanthrene-4,5- dicarboxylate |
C16 H10 O4 | others | 4.38 | 288.0415 | down | 0.000 | down | 0.000 | down | 0.000 |
22 | Se- methylselenomethionine |
C6 H14 N O2 Se | others | 11.42 | 206.0247 | up | 0.000 | up | 0.000 | up | 0.000 |
23 | sulfaphenazole | C15 H14 N4 O2 S | others | 14.16 | 336.068 | down | 0.002 | down | 0.003 | down | 0.009 |
1Control: basal diet; GseL: basal diet + 400 mg GSE/kg; GseH: basal diet + 800 mg GSE/kg; Anti: basal diet + 20 mg antibiotic/kg. 2The distinguished metabolite was up-regulated in the GseL group compared to the Control group. 3The distinguished metabolite was down-regulated in the GseH group compared to the Control group. 4The distinguished metabolite was up-regulated in the Anti group compared to the Control group. 5No statistical difference between two treatment groups.