Figure 1.

TFE3 but not TFEB affect cell proliferation of ccRCC cells. A, The relationship between TFE3/TFEB and patient prognosis in ccRCC was analysed in data from Kaplan‐Meier plotter database. B, The expression of TFE3 and TFEB in ccRCC specimens and RCC cells were analysed in data from TCGA and CCLE database. C, The expression of TFE3 and TFEB in ccRCC specimens was analysed by qPCR. D, siRNA knockdown of TFE3 and TFEB was analysed by qPCR. E, siRNA knockdown of TFE3 and TFEB was detected by Western blots. F, Cell viability was analysed using a xCELLigence RTCADP instrument. G, siRNA knockdown of TFE3 and TFEB was performed, and the cell proliferation was analysed by morphology. H, siRNA knockdown of TFE3 and TFEB was performed, and the cell proliferation was analysed by EdU. I, siRNA knockdown of TFE3 and TFEB was performed, and the cell proliferation was analysed by clone formation. Data are mean ± SD, *P < .05, **P < .01 and ***P < .001