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. 2020 Nov 2;24(23):13876–13898. doi: 10.1111/jcmm.15979

Table 2.

Cluster of AS network

Cluster Score Nodes Edges Genes
1 64.602 84 2681 PLG, ESR1, REN, TP53, NOS3, AKT1, IL6, INS, PIK3CA, TNF, FOXP3, ACE, KDR, VCAM1, PIK3CG, VEGFA, MMP9, SERPINE1, ICAM1, NOTCH1, TLR4, IFNG, SELP, CDKN2A, EDN1, EGF, NFKB1, CSF1, IGF1, MAPK1, LEP, IL4, CXCL12, ALB, F2, MMP2, IL17A, CASP1, CCL5, CAT, IL10, F3, TNFSF11, JUN, RELA, ITGAM, IL1B, BDNF, RHOA, HMOX1, SPP1, MAPK14, PTGS2, CAV1, STAT3, ANXA5, MMP1, FOS, CD34, NR3C1, TIMP1, CXCR4, BCL2, JAK2, TGFB1, MAPK8, CD40, EGR1, TNFRSF1A, SRC, TNFSF10, APOE, LDLR, CD40LG, GFAP, CTNNB1, PIK3CB, FGF2, KNG1, PPARG, CASP3, CCL2, ITGA2, SELE
2 10.133 16 76 MTHFR, CYP2C19, GSTT1, ALOX5, GSTO1, GSTA4, GSTM1, PLA2G2A, CYP2C9, GSTM3, GSTM2, GSTM4, GSTM5, DNMT1, CYP3A5, GSTP1
3 9.943 36 174 VCL, LCAT, APOA2, LPA, SDC2, HMGCR, JAG1, C3, APOC2, SREBF2, APOA5, APOA4, AGTR2, F2R, EDNRA, PLTP, ITGB2, TGFBR1, PSEN1, ITGAV, ABCG1, NPC1L1, UTS2, NR1H3, APOA1, APOC1, ABCA1, CETP, MTTP, HTR2A, NOTCH4, SERPINC1, LIPC, P2RY1, ABCG5, CYP7A1
4 9.889 37 178 F5, CHUK, SERPINF2, F8, ELANE, DUSP1, BMP4, FGB, NCF1, FGG, IL1R1, CXCR2, PPARA, ANGPT1, CFTR, PPBP, CCL11, AHSG, TXN, HMGB1, ITGA2B, ITIH4, TGFB3, CLU, CD36, MMP14, ENG, APOB, APOH, VTN, TGFB2, DCN, CDH5, FGA, PTK2, F13A1, PF4
5 8.875 33 142 AGTR1, AGT, CCR2, CCR5, PGF, FOXO3, ADIPOQ, SIRT1, IL1A, SMAD3, FLT1, NOS2, PLAT, SCARB1, SOCS1, CSF1R, TLR2, HIF1A, ACTA2, ELN, SOD2, VWF, IGFBP3, MMP3, APP, IRS1, SELL, PRL, CYBB, MPO, CRP, IL18, IKBKB
6 6 6 15 XRCC5, WRN, NBN, FEN1, RFC1, EXO1
7 5.111 10 23 MTR, TXNRD2, BHMT, AHCY, SLC10A2, CBS, MTRR, ABCC2, NR1I2, CTH
8 4.875 17 39 BCAR1, P2RY12, SREBF1, ITGB3, CYP19A1, NPY, CXCL16, SST, GNB3, PRKCA, IGFBP1, LPL, RETN, F7, PDGFB, APLN, CASR
9 4 5 8 SQSTM1, NQO1, GCLC, GCLM, KEAP1
10 4 4 6 BMP6, BMPR2, TGFBR3, ACVRL1
11 4 4 6 RAN, MGP, NDE1, SERPINB6
12 3.429 22 36 PCSK9, ADM, PROC, F10, PRKAA2, VIP, TFPI, HP, SERPIND1, CP, COG2, TTR, NR1H4, COX5A, ABCG8, NAMPT, PPARGC1A, PRKAA1, GHRL, MME, SHBG, UCP2
13 3 3 3 GPIHBP1, APOC3, ANGPTL3
14 3 3 3 SOAT1, SOAT2, CYP27A1
15 3 3 3 PDE5A, PRKAR1A, GP1BA
16 3 3 3 ALPL, COL4A1, IBSP
17 3 3 3 DYNC2LI1, COG6, ANK3
18 2.667 4 4 NFE2L2, HSPD1, SOD1, MAPK7