Figure 2.

Farnesoid X receptor (FXR) activation retards the tumour growth in nude mice. A, Image of xenograft tumours formed by Caco‐2 cells after obeticholic acid (OCA) treatment. B and C, Tumour growth curves (B) and tumour weights (C) for Caco‐2 cells after OCA treatment. D, Image of xenograft tumours formed by HT‐29 cells after OCA treatment E and F, Tumour growth curves (E) and tumour weights (F) for HT‐29 cells after OCA treatment. G and H, Immunohistochemical staining for Ki67 (G) and active caspase‐3 (H) in tumour xenografts of Caco‐2 (B) cells. I and J, Immunohistochemical staining for Ki67 (I) and active caspase‐3 (J) in tumour xenografts of HT‐29 cells. *P < .05