FIGURE 5.

Macrophage inflammatory protein (MIP)‐1α/β induced the migration of oral lichen planus (OLP) CD8⁺ T cells via CCR1 and CCR5. A, PBMCs (n = 4) passing through the pores were stained with crystal violet and assessed by IOD value. Magnification, 20×. B, The proportion of MIP‐1α/β recruited CD4⁺ and CD8⁺ T cells in the lower chambers was measured by flow cytometry. Data were presented as mean ± SEM. *, difference between the two groups. *P < 0.05, **P < 0.01. BX‐471, CCR1 inhibitor; maraviroc, CCR5 inhibitor; IOD, integrated optical density; ns, no significant difference