Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 30;24(24):14217–14230. doi: 10.1111/jcmm.16038

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

This figure shows the effect of the STEAP1 gene on cell proliferation and metastasis invivo through animal experiments. (A) The tumorigenesis experiment in nude mice shows the tumour size differences between the SGC‐7901 NC group and the sh‐STEAP1 group. (B) IHC assayshows the expression of cell proliferation‐ and inflammation‐related proteins in the tumours of nudemice (400x). (C) The difference in tumour size between the SGC‐7901 NC group and sh‐STEAP1 group in two weeks. (D) The tumour number difference between the SGC‐7901 NC group and sh‐STEAP1 group. (E) The number and distribution of abdominal tumours in 6 mice of NC group were shown. The location of mesenteric tumours was marked by the arrows (F) The number and distribution of abdominal tumours in 6 mice of sh‐STEAP1 group were shown. The location of mesenteric tumours was marked by the arrows (G) The tumours were found on the mesentery and the wall of the intestine, several larger tumours on the mesenteric and intestinal wall were marked by the arrows..(*P < .05, **P < .01, ***P < .001, ****P < .0001)