. 2020 Dec 21;175(2):e205199. doi: 10.1001/jamapediatrics.2020.5199

Table 4. Incidence Rates and HRs of First Severe Cardiovascular Event in Patients Compared to Matched Controls.

Group	No. of participants	No. of events	Person-years	Incidence rate (95% CI)^a	HR (95% CI)
Group	No. of participants	No. of events	Person-years	Incidence rate (95% CI)^a	Crude	Adjusted, simple model^b	Adjusted, full model^c
All
Controls	50 036	149	755 755	1.97 (1.68-2.32)	1 [Reference]	1 [Reference]	1 [Reference]
Patients	3408	18	51 781	3.48 (2.19-5.52)	1.75 (1.08-2.87)	1.56 (0.73-3.34)	2.27 (1.01-5.12)
Male
Controls	33 861	114	531 469	2.15 (1.79-2.58)	1 [Reference]	1 [Reference]	1 [Reference]
Patients	2305	13	36 391	3.57 (2.07-6.15)	1.66 (0.93-2.94)	1.21 (0.48-3.03)	1.92 (0.72-5.11)
Female
Controls	16 175	35	224 287	1.56 (1.12-2.17)	1 [Reference]	1 [Reference]	1 [Reference]
Patients	1103	5	15 391	3.25 (1.35-7.81)	2.08 (0.81-5.35)	3.40 (0.93-12.45)	3.68 (0.84-16.08)

Abbreviation: HR, hazard ratio.

^{^a}

Calculated as number of events per 10 000 person-years.

^{^b}

Adjusted for age and height at study start and sex.

^{^c}

Adjusted for gestational age, birth length, birth weight, age and height at study start, parental educational level, family income, and sex.