Table 4.
Determinants of Virological Failure Among Patients on ART in Central Oromia, Ethiopia, 2018
| Case | Control | COR (95%CI) | AOR (95%CI) | ||
|---|---|---|---|---|---|
| N (%) | N (%) | ||||
| Age | |||||
| ≥15 years | 192 (76.2) | 235 (93.3) | 1.00 | 1.00 | |
| <15 years | 60 (23.8) | 17 (6.7) | 4.32 (2.44–7.65) | 3.71 (1.7–8.1)** | |
| CD4 (baseline) | |||||
| ≥350 | 37 (14.7) | 56 (22.2) | 1.00 | 1.00 | |
| <100 | 60 (23.8) | 34 (13.5) | 2.67 (1.5–4.8) | 2.31 (1.1–5.1)* | |
| 100–199 | 71 (28.2) | 68 (27.0) | 1.58 (0.9–2.7) | 1.41 (0.7–2.9) | |
| 200–349 | 67 (26.6) | 82 (32.5) | 1.24 (0.7–2.1) | 1.04 (0.5–2.1) | |
| Not documented | 17 (6.7) | 12 (4.8) | 2.14 (0.9–5.0) | 0.55 (0.1–2.2) | |
| Regimen type | |||||
| TDF-3TC-EFV | 62 (24.6) | 127 (50.4) | 1.00 | 1.00 | |
| TDF-3TC-NVP | 26 (10.3) | 24 (9.5) | 2.22 (1.2–4.2) | 2.81 (1.3–6.2)** | |
| AZT-3TC-EFV | 21 (8.3) | 29 (11.5) | 1.48 (0.8–2.8) | 1.19 (0.5–2.7) | |
| AZT-3TC-NVP | 58 (23.0) | 67 (26.6) | 1.77 (1.1–2.8) | 1.18 (0.6–2.3) | |
| Other | 85 (33.7) | 5 (2.0) | 34.82 (13.4–90.2) | 35.91 (11.7–110.1) | |
| Poor adherence | |||||
| No | 161 (63.9) | 237 (94.0) | 1.00 | 1.00 | |
| Yes | 91 (36.1) | 15 (6.0) | 8.93 (5.0–16.0) | 11.19 (5.7–22.2)*** | |
| Disclosure status | |||||
| Disclosed | 205 (81.3) | 238 (94.4) | 1.00 | 1.00 | |
| Not disclosed | 47 (18.7) | 14 (5.6) | 3.89 (2.09–7.28) | 6.77 (3.2–14.2)*** | |
Notes: *P-value less than alpha (0.05), **P-value less than 0.01, ***P-value less than 0.001. All results reported in this final model were adjusted for all the variables in the table.
Abbreviations: AOR, adjusted odds ratio; COR, crude odds ratio.