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. 2020 Dec 14;15:10183–10197. doi: 10.2147/IJN.S282931

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© 2020 Zhang et al.

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Anticancer performance in vitro. (A) Viability of MG63 cells treated with free SN38, PDA-SN38 NPs or PDA-SN38@SCM NPs with or without 808-nm laser irradiation (0.6 W/cm², 5 min). (B) Live/dead staining of MG63 cells after different treatments. Calcein-AM (green, live cells) and propidium iodide (PI) (red, apoptotic cells). (1) Control, (2) SN38, (3) PDA, (4) PDA-SN38, (5) PDA-SN38@SCM, (6) 808-nm laser irradiation, (7) SN38 plus 808-nm laser irradiation, (8) PDA NPs plus 808-nm laser irradiation, (9) PDA-SN38 NPs plus 808-nm laser irradiation and (10) PDA-SN38@SCM NPs plus 808-nm laser irradiation. Scale bar = 200 μm. ***p < 0.001.