Table 1.
Comparison of outcome data between patients treated with low and high PEEP H‐CPAP
| High PEEP H‐CPAP | Low PEEP H‐CPAP | P value | |
|---|---|---|---|
| Outcome data | |||
| 1PICU survival, n (%) | 61.0 (98.4) | 23.0 (100.0) | 1.000 |
| 2LOS, (d) | 6.0 ± 2.2 | 10.3 ± 6.6 | .001 |
| 1Pneumothorax, n (%) | 0.0 | 0.0 | n.a. |
| 1Endotracheal intubation, n (%) | 1.0 (1.6) | 11.0 (47.8) | <.001 |
| Haemodynamic and respiratory data after 1 h of treatment | |||
| 2Systolic blood pressure, mm Hg | 87.0 ± 3.3 | 90.0 ± 12.7 | .482 |
| 2Diastolic blood pressure, mm Hg | 45.0 ± 4.2 | 50.8 ± 10.3 | .192 |
| 2Heart rate, beats/min | 146.0 ± 5.5 | 153.6 ± 14.4 | .131 |
| 2Change in heart rate, beats/min | −31.2 ± −14.4 | −21.4 ± −22.4 | .036 |
| 2Respiratory rate, breaths/min | 52.0 ± 1.8 | 56.2 ± 10.7 | .053 |
| 2Change in respiratory rate, breaths/min | −14.0 ± 5.1 | −5.8 ± −13.6 | .005 |
| 2pH | 7.31 ± 0.02 | 7.27 ± 0.07 | .083 |
| 2PaCO2, mm Hg | 54.0 ± 3.3 | 58.1 ± 13.9 | .274 |
| 2PaO2/FiO2 | 178.0 ± 13.2 | 149.2 ± 23.9 | <.001 |
| 3Change in PaO2/FiO2 | 44.5 [34.5;53.0] | 34.0 [22.0;39.2] | .001 |
| Haemodynamic and respiratory data after 24 h of treatment | |||
| 2Systolic blood pressure, mm Hg | 85.0 ± 5 | 94.8 ± 11.2 | .012 |
| 2Diastolic blood pressure, mm Hg | 45.0 ± 3.4 | 52.6 ± 10.9 | .024 |
| 3Heart rate, beats/min | 140.0 [134.0;145.0] | 140.0 [134.0;144.5] | .847 |
| 2Change in heart rate, beats/min | −39.9 ± 16.7 | −32.6 ± 17.0 | .174 |
| 3Respiratory rate, breaths/min | 44.0 [38.0;46.0] | 45.5 [38.5;60.0] | .091 |
| 2Change in respiratory rate, breaths/min | −22.0 ± 4.7 | −13.1 ± 11.7 | .006 |
| 3pH | 7.40 [7.36;7.41] | 7.42 [7.38;7.43] | .223 |
| 3PaCO2, mm Hg | 46.0 [44.0;50.0] | 46.0 [39.0;46.0] | .391 |
| 2PaO2/FiO2 | 220.0 ± 12.4 | 205.8 ± 42.6 | .042 |
| 3Change in PaO2/FiO2 | 90.0 [77.0;101.5] | 66.0 [57.7;94.5] | .040 |
Values are given as 1numbers and percentages, 2means and standard deviations, or 3medians and interquartile range. Analyses SPSS, version 15.0 (SPSS Inc, Illinois, USA): Shapiro‐Wilk test (normality of data), Student t test (normally distributed continuous variables), Mann‐Whitney test (non‐normally distributed variables), chi‐square test (categorical variables).