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. 2020 Jul 24;21(22):3197–3207. doi: 10.1002/cbic.202000381

Figure 2.

Figure 2

Morphological profiling of references linked to iron chelation that shared high biosimilarity to DFO. A) Structures of annotated iron chelators. B) Fingerprints of iron chelators at 10 μM visualized as line plots and heatmap. The top line of the heatmap profile is set as a reference fingerprint (100 % BioSim) to which the following fingerprints are compared. The set of 579 parameters is divided in parameters related to the cell (1–229), cytoplasm (230–461) and nuclei (462–579). Values were normalized to the DMSO control. Blue: decreased parameter, red: increased parameter.