. 2020 Dec 15;11(12):596–610. doi: 10.4239/wjd.v11.i12.596

Table 5.

The relationships of glycemic control indicators, plasma creatinine and urinary albumin-to-creatinine ratio with renal structural parameters

Parameter	Fructosamine	Glycated albumin	Plasma creatinine	UACR
Mesangial volume, V_V	r = 0.69	r = 0.67	r = 0.57	r =0.81
Mesangial volume, V_V	P = 0.0002	P = 0.0004	P = 0.004	P = 0.000002
Capillary volume, V_V	r = 0.13	r = 0.11	r = 0.30	r = 0.05
Capillary volume, V_V	P > 0.05	P > 0.05	P > 0.05	P > 0.05
GBM width	r = 0.69	r = 0.69	r = 0.21	r = 0.53
GBM width	P = 0.0008	P = 0.007	P > 0.05	P = 0.02
Podocyte FPs, width	r = 0.62	r = 0.63	r = –0.15	r = 0.50
Podocyte FPs, width	P = 0.003	P = 0.003	P > 0.05	P = 0.03
Podocyte FPs, N_A	r = –0.57	r = -0.58	r = 0.04	r = –0.25
Podocyte FPs, N_A	P = 0.008	P = 0.007	P > 0.05	P > 0.05
Nephrin-positive areas in glomeruli, V_V	r = –0.68	r = –0.65	r = –0.51	r = –0.76
Nephrin-positive areas in glomeruli, V_V	P = 0.006	P = 0.009	P = 0.04	P = 0.001
TGF-β positive areas in glomeruli, V_V	r = 0.65	r = 0.65	r = 0.09	r = 0.67
TGF-β positive areas in glomeruli, V_V	P = 0.003	P = 0.002	P >0.05	P = 0.001

UACR: Urinary albumin-to-creatinine ratio; GBM: Glomerular basement membrane; FPs: Foot processes; Vv: Volumetric density; TGF-β: Transforming growth factor β. Spearman’s rank correlation coefficients are shown.