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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: NMR Biomed. 2020 Mar 3;33(5):e4283. doi: 10.1002/nbm.4283

Figure 1 -. 3D FLAIR* images obtained on Siemens (Lausanne University Hospital; A,B) and Philips (Erasmus University Hospital; C,D) MRI scanners showing central vein sign positive (CVS+) and negative (CVS-) lesions.

Figure 1 -

A central vein running through the lesion (arrows) is visible in the majority of white matter lesions in a 28-year-old man (A) and 27-year-old woman (C) with relapsing-remitting MS. Images from 25-year-old (B) and 46-year-old (D) women with Sjögren syndrome show how the central vein sign is not typical of white matter lesions in MS-mimicking diseases.