Table 3.
Correlation of lncRNAs with kidney function (eGFR), diabetes (HbA1c), and vascular injury markers sTM, Ang‐2, and angiogenic miRNAs
| MALAT1 | LNC‐EPHA6 | LIPCAR | LNC‐RPS24 | |
|---|---|---|---|---|
| eGFR (mL/min/1.73 m2) | −0.198 (ns) | −0.244 (ns) | −0.412 (P = .003) | −0.132 (ns) |
| HbA1c (mmol/mol) | 0.357 (P = .010) | 0.244 (ns) | 0.218 (ns) | 0.095 (ns) |
| Vascular injury markers | ||||
| sTM | 0.250 (ns) | 0.284 (P = .031) | 0.342 (P = .009) | 0.091 (ns) |
| Ang‐2 | 0.069 (ns) | −0.015 (ns) | 0.030 (ns) | −0.200 (ns) |
| Angiogenic miRNAs | ||||
| miR‐25 | −0.062 (ns) | −0.409 (P = .02) | 0.320 (ns) | −0.301 (ns) |
| miR‐27a | 0.384 (P = .05) | 0.670 (P < .001) | 0.616 (P < .001) | −0.006 (ns) |
| miR‐126 | −0.128 (ns) | 0.074 (ns) | 0.056 (ns) | 0.006 (ns) |
| miR‐130b | 0.539 (P < .001) | 0.711 (P < .001) | 0.658 (P < .001) | 0.026 (ns) |
| miR‐132 | 0.243 (ns) | 0.361 (ns) | 0.285 (ns) | 0.221 (ns) |
| miR‐152 | 0.447 (P = .004) | 0.557 (P < .001) | 0.503 (P < .001) | −0.024 (ns) |
| miR‐181a | 0.074 (ns) | 0.247 (ns) | 0.216 (ns) | 0.052 (ns) |
| miR‐223 | −0.297 (ns) | 0.004 (ns) | −0.095 (ns) | 0.002 (ns) |
| miR‐320 | 0.252 (ns) | 0.232 (ns) | 0.269 (ns) | 0.118 (ns) |
| miR‐326 | 0.082 (ns) | 0.245 (ns) | 0.261 (ns) | 0.084 (ns) |
| miR‐340 | 0.532 (P < .001) | 0.657 (P < .001) | 0.603 (P < .001) | −0.011 (ns) |
| miR‐574 | −0.332 (ns) | −0.240 (ns) | −0.273 (ns) | 0.070 (ns) |
| miR‐660 | 0.319 (ns) | 0.109 (ns) | 0.119 (ns) | 0.169 (ns) |
Values represent correlation coefficients and P‐values. Bold values are significant correlations (P < 0.05).
Abbreviations: Ang‐2, angiopoietin‐2; sTM, soluble thrombomodulin.