TABLE 1.
Demographics and disease characteristics patients at baseline ‐ TTS
| Ig‐naïveN = 23 | Ig‐pre‐treatedN = 20 | OverallN = 43 | |
|---|---|---|---|
| Age (years) | |||
| Mean ± SD | 48.7 ± 15.8 | 55.8 ± 15.0 | 52.0 ± 15.7 |
| Median | 48.0 | 59.0 | 50.0 |
| Min‐max | 21‐78 | 24‐79 | 21‐79 |
| Gender, N (%) | |||
| Male | 12 (52.2%) | 12 (60.0%) | 24 (55.8%) |
| Female | 11 (47.8%) | 8 (40.0%) | 19 (44.2%) |
| Body mass index (kg/m2) | |||
| Mean ± SD | 25.6 ± 4.8 | 24.3 ± 4.4 | 25.0 ± 4.6 |
| Median | 25.4 | 24.6 | 25.1 |
| Min‐max | 18.2‐40.0 | 14.3‐31.9 | 14.3‐40.0 |
| Diagnostic categories of CIDP, N (%) a | |||
| Definite | 20 (87%) | 20 (100%) | 40 (93%) |
| Probable | 3 (13%) | 0 | 3 (7%) |
| Time since first symptoms (years) | |||
| Mean ± SD | 6.7 ± 7.4 | 6.7 ± 5.6 | 6.7 ± 6.5 |
| Median | 3.6 | 3.4 | 3.4 |
| Min‐max | 0.4‐28.6 | 0.4‐17.3 | 0.4‐28.6 |
| Time since diagnosis (years) | |||
| Mean ± SD | 2.7 ± 6.0 | 5.0 ± 5.5 | 3.8 ± 5.8 |
| Median | 0.2 | 2.4 | 1.2 |
| Min‐max | 0.0 b ‐23.3 | 0.0 c ‐16.8 | 0.0 c ‐23.3 |
| Total adjusted INCAT disability score | |||
| Mean ± SD | 2.7 ± 1.3 | 3.3 ± 1.8 | 3.0 ± 1.5 |
| Median | 2.0 | 2.5 | 2.0 |
| Min‐max | 2‐6 | 2‐8 | 2‐8 |
Note: Range of total adjusted INCAT disability score: 0 (normal) to 9 (maximum disability). Range of adjusted INCAT disability arms score: 0 to 4. Range of adjusted INCAT disability legs score: 0 to 5.
Abbreviations: CIDP, chronic inflammatory demyelinating polyneuropathy; INCAT, inflammatory neuropathy cause and treatment; N, number of patients; TTS, total treated set.
CIDP diagnosis was considered as definite or probable according to the EFNS/PNS guidelines 2010 clinical and neurophysiological criteria.
The minimal values of 0.0 years correspond to periods of time < 18 days (since Min values were documented in year with only one decimal).
In the Ig‐pre‐treated subgroup, one patient had been pre‐treated 5 months before by Ig for CIDP symptoms, but the diagnosis was confirmed only 4 days before the inclusion in the study explaining the value 0.0 year for time since diagnosis.