Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Simcyp Preliminary Prediction for Ketoconazole and Rifampicin Effects on Molibresib PK Parameters
| Predicted ratio (5th and 95th percentiles) | ||
|---|---|---|
| Parameter | Ketoconazole | Rifampicin |
| Cmax | 1.29 (1.26‐1.32) | 0.61 (0.58‐0.64) |
| AUC | 4.7 (4.39‐5.03) | 0.24 (0.23‐0.26) |
Cmax, maximum concentration; AUC, area under the curve from 0 to infinity.
