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. 2020 Sep 10;15(22):2121–2135. doi: 10.1002/cmdc.202000391

Figure 10.

Figure 10

(a) Structure of palbociclib. (b) Representative images of ovarian cancer A2780 xenografted tumours isolated from mice following treatments with olaparib, palbociclib or both. (c) The tumour volume of A2780 xenografted mice in the respective mentioned groups, with the arrow indicating the starting date of the treatment. Reprinted from EBioMedicine, 43, Yi, J. et al., MYC Status as a Determinant of Synergistic Response to Olaparib and Palbociclib in Ovarian Cancer, 225–237, Copyright 2019, with permission from Elsevier.