Figure 12.

(a) Structures of antirheumatic agent, Auranofin and three Au(III) compounds (Aubipy, Auphen and Au−C−N). (b) Gold finger formation. Example of the possible binding of Au−C−N with the zinc finger domain of PARP1, in which two chlorido ligands of Au−C−N have been replaced by two cysteinato groups. Figure (b) adapted from reference 152 under the terms of the Creative Commons Attribution 3.0 Unported Licence (https://creativecommons.org/licenses/by/3.0/). Published by The Royal Society of Chemistry. © The Author 2018.