TABLE 2.
Trends in number of patients diagnosed and initial treatment over time
| Total population | Year of diagnosis | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | ||
| No. of patients diagnosed with CRC (any stage) 25 | 123 190 | 12 150 | 12 311 | 12 773 | 13 210 | 13 256 | 13 057 | 15 214 | 15 913 | 15 306 |
| No. of patients diagnosed with stage IV CRC (% of all CRC patients) | 27 275 (22%) | 2807 (23%) | 2844 (23%) | 3030 (24%) | 3086 (23%) | 3044 (23%) | 3198 (25%) | 3176 (21%) | 3097 (20%) | 2993 (20%) |
| Percentage of stage IV patients deceased at end of FU a | 24 342 (89%) | 2665 (95%) | 2691 (95%) | 2850 (94%) | 2848 (92%) | 2798 (92%) | 2889 (90%) | 2756 (87%) | 2564 (83%) | 2281 (76%) |
|
Treatment modalities (% of stage IV patients) b | ||||||||||
| No antitumor therapyB | 6081 (22%) | 630 (22%) | 643 (23%) | 705 (23%) | 649 (21%) | 706 (23%) | 720 (23%) | 646 (20%) | 677 (22%) | 705 (24%) |
| Systemic therapy ± PTRD | 12 240 (45%) | 1299 (46%) | 1329 (47%) | 1383 (46%) | 1422 (46%) | 1354 (45%) | 1465 (46%) | 1443 (45%) | 1318 (43%) | 1227 (41%) |
| Systemic therapy onlyE | 7245 (27%) | 665 (24%) | 786 (28%) | 786 (26%) | 809 (26%) | 799 (26%) | 853 (27%) | 901 (28%) | 822 (27%) | 824 (28%) |
| Systemic therapy + PTRF | 3768 (14%) | 523 (19%) | 436 (15%) | 455 (15%) | 471 (15%) | 435 (14%) | 449 (14%) | 396 (13%) | 351 (11%) | 252 (8%) |
| Metastasectomy/HIPEC + systemic therapyG | 2956 (11%) | 213 (8%) | 260 (9%) | 294 (10%) | 371 (12%) | 375 (12%) | 389 (12%) | 371 (12%) | 383 (12%) | 300 (10%) |
| Metastasectomy/HIPEC onlyH | 1564 (6%) | 109 (4%) | 95 (3%) | 124 (4%) | 118 (4%) | 119 (4%) | 153 (5%) | 238 (8%) | 270 (9%) | 338 (11%) |
Note: B, D, E, F, G, and H correspond to the graphs in Figure 2.
Abbreviations: CRC, colorectal cancer; FU, follow‐up; HIPEC, hyperthermic intraperitoneal chemotherapy; PTR, primary tumor resection.
a
31 January 2019.
b
The percentages for the treatment modalities do not add up to 100% because the categories are not all mutually exclusive.