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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Genet Epidemiol. 2020 Aug 30;44(8):908–923. doi: 10.1002/gepi.22351

Figure 4.

Figure 4.

Empirical power of MAGEE tests on quantitative traits in 20,000, 50,000, and 100,000 related samples. (A) Scenario 1: 80% null variants, 10% causal variants with positive effects and 10% causal variants with negative effects for both genetic main effects and GEI effects. (B) Scenario 2: 80% null variants, 10% causal variants with positive effects and 10% causal variants with negative effects for genetic main effects only. (C) Scenario 3: 80% null variants, 10% causal variants with positive effects and 10% causal variants with negative effects for GEI effects only. (D) Scenario 4: 80% null variants, 16% causal variants with positive effects and 4% causal variants with negative effects for both genetic main effects and GEI effects. (E) Scenario 5: 80% null variants, 16% causal variants with positive effects and 4% causal variants with negative effects for genetic main effects only. (F) Scenario 6: 80% null variants, 16% causal variants with positive effects and 4% causal variants with negative effects for GEI effects only.