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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Genet Epidemiol. 2020 Aug 30;44(8):908–923. doi: 10.1002/gepi.22351

Table 1.

A brief summary of GEI tests and joint tests within the MAGEE framework.

Test Type Analogya
GEI tests Interaction variance component (IV) test Variance component test rareGE GEI test
Interaction hybrid test using Fisher’s (IF) method Hybrid of burden and variance component tests MiSTi
Joint tests Joint variance component (JV) test Variance component test rareGE JOINT test
Joint hybrid test using Fisher’s (JF) method Hybrid of burden and variance component tests N/Ab
Joint hybrid test using double Fisher’s (JD) procedures Hybrid of burden and variance component tests N/Ab
a

Analogy in unrelated samples.

b

N/A: Not applicable.