Figure 1.

Effect of different diuretic application approaches (IDU vs. CDU) on all‐cause mortality, cardiovascular death, and cerebrovascular death. Model 1: adjusting for baseline adjustment covariates, including age, gender, smoking, drinking, rheumatic heart disease course, New York Heart Association functional classification, cardiac valve damage, surgical intervention, medical condition (hypertension, coronary heart disease, type 2 diabetes mellitus, atrial fibrillation, and stroke), combined medication (antiplatelet drugs, warfarin, digoxin, nitrates, renin‐angiotensin system inhibitors, beta‐receptor blockers, mineralocorticoid receptor antagonists, calcium channel blockers, and statins), types of diuretics, cumulative use time, blood biochemical index (white blood cell count, haemoglobin, serum sodium, serum potassium, creatinine, haemoglobin A1C, and C‐reactive protein), and echocardiography (left atrial end‐systolic diameter, left ventricular end‐diastolic diameter, right ventricular end‐diastolic diameter, and right atrial end‐systolic diameter). CI, confidence interval; CDU, continuous diuretics use; HR, hazard ratio; IDU, intermittent diuretics use.