Table 1.

Demographic Information, Laboratory Data at Index Visit, and Mitochondrial DNA Haplogroup Frequencies

Variables	Overall	HIV Seronegative, n = 355	HIV Seropositive, n = 933	P Valuea
Age	39.6 (33.3–46.2)	38.3 (29.0–45.5)	40.0 (34.2–46.4)	<.01
BMI, kg/m2	27.8 (23.6–33.1)	28.2 (23.5–33.6)	27.6 (23.7–33.0)	.65
CD4 + count, cells/mm3	515 (317–765)	912 (752–1191)	444 (280–635)	<.01
Detectable plasma HIV RNA, >400 cps/mL	…	…	505 (54)
On ART at index visit	…	…	500 (54)
Plasma HIV RNA, copies/mL	…	…	770 (80–9900)
Total cholesterol, mg/dL	175 (15–202)	177 (152–202)	174 (150–203)	.43
LDL cholesterol, mg/dL	99 (79–126)	99 (82–125)	99.0 (79–126)	.99
HDL cholesterol, mg/dL	50 (40–62)	56 (46–66)	48 (37–60)	<.01
Triglycerides, mg/dL	94 (68–139)	77 (56–111)	101 (73–150)	<.01
Glucose, mg/dL	84 (78–91)	83 (76–91)	84 (78–91)	.09
Insulin, mlU/L	10 (6–16)	8 (5–15)	10 (6–17)	<.01
HOMA-IR	2.0 (1.2–3.5)	1.7 (1.0–3.1)	2.1 (1.3–3.6)	<.01
HOMA-B	171.8 (110.2–276.1)	152.9 (100.2–253.1)	180.0 (114.5–288.0)	<.01
African mtDNA haplogroups
L0L1	300 (23.3)	81 (22.8)	219 (23.5)	.30
L2	367 (28.5)	98 (27.6)	269 (28.8)
L3	478 (37.1)	127 (35.8)	351 (37.6)
Other	143 (11.1)	49 (13.8)	94 (10.1)

Data are among non-Hispanic, Black WIHS participants, by HIV serostatus. Values shown are median (IQR) or n (%), unless otherwise indicated.

Abbreviations: ART, antiretroviral therapy; BMI, body mass index; HDL, high-density lipoprotein; HIV, human immunodeficiency virus; HOMA-B, homeostatic model assessment of β-cell function; HOMA-IR, homeostatic model assessment of insulin resistance; IQR, interquartile range; LDL, low-density lipoprotein; mtDNA, mitochondrial DNA; WIHS, Women’s Interagency HIV Study.

^aThe P values were evaluated by the χ2 test for categorical variables and the Wilcoxon-Mann-Whitney test for continuous variables.