Table 1.
Patients with complete data on all baseline variables
| Overall (n = 4495) | HFpEF (n = 589) | HFrEF (n = 513) | Non‐HF (n = 3393) | P value | |
|---|---|---|---|---|---|
| Age (years) | 62 (53–68) | 67 (61–74) | 65 (58–72) | 60 (51–67) | <0.001 |
| Male | 3100 (68.97) | 308 (52.29) | 334 (65.11) | 2458 (72.44) | <0.001 |
| BMI (kg/m2) | 24.69 (22.49–27.34) | 24 (21.85–26.63) | 24.80 (22.12–27.07) | 24.93 (22.82–27.46) | <0.001 |
| Smoking (current + ex) | 2913 (64.81) | 341 (57.89) | 301 (58.67) | 2271 (66.93) | <0.001 |
| Previous history | |||||
| Hypertension | 2361 (52.53) | 353 (59.93) | 284 (55.36) | 1724 (50.81) | <0.001 |
| Diabetes | 1074 (23.89) | 154 (26.15) | 164 (31.97) | 756 (22.28) | 0.942 |
| MI | 440 (9.79) | 63 (10.70) | 94 (18.32) | 283 (8.34) | 0.176 |
| AMI types | |||||
| STEMI | 3062 (68.12) | 392 (66.55) | 369 (71.93) | 2301 (67.82) | 0.018 |
| CAG | 3280 (96.67) | 579 (98.30) | 486 (94.74) | 3280 (96.67) | <0.001 |
| Multivessel disease | 2002 (44.54) | 316 (53.65) | 309 (60.23) | 1377 (40.58) | <0.001 |
| PCI | 3732 (83.03) | 505 (85.74) | 426 (83.04) | 2801 (82.55) | 0.003 |
| LVEDd (mm) | 46 (42.90–49) | 45.50 (42.30–48.30) | 52.60 (48–57) | 45.60 (42.60–48.30) | 0.06 |
| EF (%) | 61 (54–62) | 59 (55–62) | 40.80 (36–45) | 61 (57–63) | <0.001 |
| Laboratory covariates | |||||
| eGFR (mL/min/1.73 m2) | 82.11 (66.14–97.06) | 69.07 (49.66–84.28) | 67.93 (51.51–86.64) | 85.97 (71.16–99.55) | <0.001 |
| cTNI (ng/L) | 32.22 (8.95–93.37) | 41.39 (12.34–122.51) | 61.98 (13.88–149.91) | 28.64 (7.93–80.91) | <0.001 |
| NT‐proBNP (pmol/L) | 996 (342.50–2599.50) | 4535 (1775–6835) | 5653 (2811–10 694) | 669 (243–1461) | <0.001 |
| Hs‐CRP (mg/L) | 5.75 (2.34–12.02) | 10.27 (3.51–13.63) | 12.06 (6.46–14.12) | 4.70 (2.02–10.92) | <0.001 |
| D‐dimer (ng/mL) | 102 (59–201) | 145 (87–289) | 185 (101–433) | 88 (52–166) | <0.001 |
| TG (mmol/L) | 1.38 (0.97–1.97) | 1.32 (0.93–1.89) | 1.29 (0.96–1.78) | 1.41 (0.98–2.02) | <0.001 |
| TC (mmol/L) | 4.54 (3.90–5.27) | 4.41 (3.76–5.24) | 4.30 (3.67–5.13) | 4.58 (3.95–5.31) | 0.008 |
| Medical treatment | |||||
| Aspirin | 4363 (97.06) | 566 (96.10) | 469 (91.42) | 3328 (98.08) | <0.001 |
| Clopidogrel or Ticagrelor | 4685 (97.2) | 571 (96.94) | 470 (91.62) | 3341 (98.47) | <0.001 |
| Statins | 4324 (96.20) | 563 (95.59) | 463 (90.25) | 3298 (97.20) | 0.185 |
| ACEI/ARB | 3312 (73.68) | 447 (75.89) | 376 (73.29) | 2489 (73.36) | <0.001 |
ACE, angiotensin converting enzyme; ARB, angiotensin II receptor blocker; BMI, body mass index; CAG, coronary angiography; cTnI, cardiac troponin I; EF, ejection fraction; eGFR, estimated glomerular filtration rate; Hs‐CRP, high sensitivity C reactive protein; LVEDd, left ventricular end‐diastolic dimension; NT‐proBNP, amino‐terminal pro‐B‐type natriuretic peptide; PCI, percutanous coronary intervention; STEMI, ST‐segment elevation myocardial infarction; TC, total cholesterol; TG, triglyceride.
Values are median (25th and 75th percentile) or number (percentages).