Table 3.
Hazard ratios (95% confidence intervals) associated with D‐dimer for outcomes in patients with AMI in different HF groups
| D‐dimer <145 ng/mL | D‐dimer ≥145 ng/mL | P value | 1‐SD increase in D‐dimer | P value | |
|---|---|---|---|---|---|
| All patients | |||||
| Unadjusted | 1 | 3.12 (2.38, 4.10) | <0.001 | 1.60 (1.44, 1.78) | <0.001 |
| Adjusted model | 1 | 1.61 (1.20, 2.17) | 0.002 | 1.20 (1.04, 1.37) | 0.01 |
| HFpEF | |||||
| Unadjusted | 1 | 3.46 (1.89, 6.31) | <0.001 | 1.79 (1.41, 2.26) | <0.001 |
| Adjusted model | 1 | 2.09 (1.08, 4.02) | 0.02 | 1.43 (1.05, 1.94) | 0.024 |
| HFrEF | |||||
| Unadjusted | 1 | 2.27 (1.46, 3.53) | <0.001 | 1.34 (1.14, 1.58) | <0.001 |
| Adjusted model | 1 | 1.25 (0.76, 2.04) | 0.37 | 0.97 (0.78, 1.21) | 0.81 |
| Non‐HF | |||||
| Unadjusted | 1 | 3.77 (2.51, 5.66) | <0.001 | 1.92 (1.62, 2.28) | <0.001 |
| Adjusted model | 1 | 1.56 (0.98, 2.47) | 0.06 | 1.40 (1.10, 1.77) | 0.001 |
Unadjusted model adjusted for: none. Adjusted model adjusted for: sex, age, BMI, smoking status, AMI‐types and the histories of hypertension, diabetes, and myocardial infarction, NT‐proBNP, cTNI, hs‐CRP, eGFR, TC, PCI, and medical treatments including aspirin, clopidogrel or ticagrelor, and statins.