. 2020 Sep 10;7(6):3561–3572. doi: 10.1002/ehf2.12769

Table 3.

Association between rs2070600 variant and prognosis of chronic heart failure

SNP rs ID	Analysis model	Dominant ^a		Recessive ^b		Additive ^c
(M > m)	Analysis model	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
rs2070600 (G > A)	Crude	0.84 (0.70–1.02)	0.074	0.49 (0.28–0.87)	0.015 ^*	0.53 (0.30–0.92)	0.024 ^d , ^*
	Adjusted	0.86 (0.71–1.04)	0.113	0.53 (0.45–1.14)	0.030 ^*	0.59 (0.34–1.03)	0.064 ^d
	Adjusted	0.86 (0.71–1.04)	0.113	0.53 (0.45–1.14)	0.030 ^*	0.91 (0.75–1.10)	0.332 ^e

M, major allele; m, minor allele; SNP, single nucleotide polymorphism.

Hazard ratio (HR) and 95% confidence intervals (95% CI) were obtained by Cox regression analysis, with or without adjustment for sex, age, hypertension, diabetes, hyperlipidaemia and smoking status, beta blocker use.

^{^a}

Dominant (GGvsAG+AA).

^{^b}

Recessive (AAvsAG+GG).

^{^c}

Additive (AAvsAGvsGG).

^{^d}

In additional model AA vs. GG.

^{^e}

AG vs. GG.

^{^*}

P < 0.05.