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Analysis of Pharmacokinetic/Pharmacodynamic Predictors of Cure of Pharyngeal Gonorrhea With 360 mg Intramuscular Gentamicin
| Predictor | Cure (n = 2) | Failure (n = 8) | P Value |
|---|---|---|---|
| Gentamicin MIC, μg/mL, median | 8 | 8 | .486 |
| Gentamicin Cmax, μg/mL, mean | 18.9 | 22.5 | .470 |
| Gentamicin weight-based dosing, mg/kg, mean | 4.26 | 4.80 | .596 |
| Cmax/MIC ratio, mean | 2.36 | 3.71 | .345 |
| Cmax/MIC ratio, geometric mean | 0.851 | 1.23 | .280 |
Abbreviations: Cmax, peak serum concentration; MIC, minimum inhibitory concentration.
