Central Illustration.

Cardiovascular Disease Burden Across Time, Location, Cause, and Risk Factor

Percent Change in Age-Standardized CVD Death Rate from 2010-2019. Map of the percent change in age-standardized CVD mortality rate from 2010 to 2019.Number of CVD Deaths. Total number of deaths due to CVD by sex, 1990 to 2019; total number of deaths due to CVD in 2010 and 2019 among the countries with the highest number of CVD deaths in 2019. Proportion of CVD Deaths by Cause (2019). Proportion of total CVD deaths in 2019 by underlying causes. CVD Burden Attributable to Modifiable Risk Factors. Comparison of the rankings of CVD DALYs attributable to modifiable risk factors in 1990 and 2019. CVD = cardiovascular disease; DALYs = disability-adjusted life years; LDL = low-density lipoprotein.