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Adjusted least square mean IOPs plotted over the entire study time for normal (A) and glaucomatous dogs (B). While there was a trend towards lower IOPs in netarsudil vs. BSS treated eyes, these differences were significant at only few time points with q24h- and q12h-treatment as well as during the washout period. The vertical lines indicate the 8am time points of each day when diurnal data collection was performed. Significance: *, p<0.05.
