Figure 2.

Longitudinal change in bone resorption outcomes by treatment arm. A, Model-based mean longitudinal changes in CTx by treatment arm and weeks on study. B, Model-based mean CTx percentage change from baseline by treatment arm and weeks on study. C, Model-based mean longitudinal changes in osteocalcin by treatment arm and weeks on study. D, Model-based mean osteocalcin percentage change from baseline by treatment arm and weeks on study. For each of the 4 panels, the vertical bars are the 95% confidence intervals and the numbers below time points signify the number of subjects in each treatment group at each time interval. Abbreviations: ART, antiretroviral therapy; CTx, C-terminal telopeptide of collagen; PL, active placebo; ZOL, zoledronic acid.