Permutations of cMRF acquisition patterns tested in simulations. (A) Six classes of flip angle distributions were used. As described in the main text, for each distribution, simulations were repeated after scaling the entire flip angle series to reach maximum values of 15°, 25°, 50°, and 75°. (b) Three TR distributions were tested. (c) Three schedules of magnetization preparation pulses were investigated. As described in the main text, PREP-4 and PREP-5 schedules were simulated using inversion times and T2 preparation times that were either repeating or non-repeating.