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. 2020 Dec 15;12(1):1854923. doi: 10.1080/19420862.2020.1854923

Table 2.

Relative abundances of doubly cysteinylated IgG2-A form (%2Cys) in endogenous IgG2s purified from healthy human serum. XICdoubly cysteinylated and XICclassically linked are the extracted ion chromatogram peak areas of the precursor/product ion transitions for the doubly cysteinylated and classically linked IgG2-A Lys-C dipeptides, respectively. Demographic information corresponding to each human subject is included. There was no obvious correlation between hinge cysteinylation levels and age, gender or race, granted the sample size was small

Gender Race Age XICclassically linked XICdoubly cysteinylated %2Cys
Male White 52 21214823 96558 0.5
Male Hispanic 66 15023572 139367 0.9
Male White 59 9312008 78597 0.8
Male Black 58 15631974 94021 0.6
Male White 44 17710870 159266 0.9
Female White 44 25823084 160364 0.6
Female Hispanic 63 17255965 204560 1.2
Female White 63 23764328 142695 0.6
Female White 58 15456256 72583 0.5
Female Black 63 17672827 229390 1.3
      Average 0.8
      Standard Deviation 0.3