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Versatility and scalability of DBM linkers. (A) HIC traces of ADCs derived from conjugation of 2 (DBM-MMAF) with 3 different commercially available antibodies: Avastin, Rituxan, and Erbitux. (B) HIC traces of ADCs resulting from conjugation of 2 with IGNX at 3 different reaction scales (1 mg, 25 mg, and 1000 mg).
