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. 2020 Dec 18;13:713–724. doi: 10.2147/JAA.S281198

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© 2020 Li et al.

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Metabolic pathway analysis of differential metabolites identified from asthma patients compared with healthy controls. (A) Significantly changed pathways based on enrichment and topology analyses: sphingolipid metabolism (a), citrate cycle (b), valine, leucine, and isoleucine biosynthesis (c), propanoate metabolism (d), aminoacyl–tRNA biosynthesis (e), tyrosine metabolism (f), glycine, serine, and threonine metabolism (g), glyoxylate and dicarboxylate metabolism (h), cysteine and methionine metabolism (i), and alanine, aspartate, and glutamate metabolism (j). (B) Functional enrichment analysis of pathways. Color depth and column length indicate degree of disturbance.