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. 2020 Dec 18;13:12965–12977. doi: 10.2147/OTT.S279710

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© 2020 Lin et al.

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Differential expression of circRNAs in plasma exosomes from patients with LUAD. (A) Heat map with each column representing a blood sample and each row representing a differentially expressed circRNA. Red color represents the upregulated circRNAs, whereas green represents downregulated circRNAs. (B) Volcano plots of differential expression of circRNAs between LUAD and normal control plasma samples. The red squares show the differentially expressed circRNAs identified by circRNA sequencing. The vertical line marks the twofold (log2 scaled) up or down changes. The horizontal line marks the p-value of 0.05 (−log10 scaled). (C) Scatter plots of the distribution of circRNAs.