Skip to main content
. Author manuscript; available in PMC: 2021 Sep 10.
Published in final edited form as: J Med Chem. 2020 Aug 25;63(17):9237–9257. doi: 10.1021/acs.jmedchem.0c00310

Scheme 2.

Scheme 2.

Synthesis of ureas 12 and 14.a

aReagents and conditions: a) Triphosgene, sat. NaHCO3, DCM, 30 min; b) 11, DCM, overnight, 52% overall yield; c) 13, DCM, overnight, 24% overall yield. See Experimental Section and Supporting Information for further details.