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. Author manuscript; available in PMC: 2020 Dec 22.
Published in final edited form as: J Biol Rhythms. 2020 Jun 8;35(4):368–376. doi: 10.1177/0748730420929450

Figure 1.

Figure 1.

Effect of environmental circadian disruption schedules on cerebral infarction after transient focal ischemia with middle cerebral artery occlusion in mice. Infarct volume of each ipsilateral hemisphere as a percentage of the contralateral hemisphere in cresyl violet–stained coronal brain slices. (A) Control (constant 12:12 light cycle; n = 9); (B) 4 week advance, 1 week static (n = 13); (C) 4 week advance, 3 week static (n = 14); (D) 1 week advance, 1 week static (n = 12); (E) 4 week delayed, 1 week static (n = 11). One representative example from each group is also shown. Values are significantly different (Kruskal-Wallis nonparametric analysis of variance, p = 0.011; Dunn’s post hoc analysis, p < 0.05) between the control group (A) and 4 weeks advanced, 1 week static group (B).