Table 2.
Description | Gene markers | GBM | |||||||||||||||
E2F1 | E2F2 | E2F3 | E2F4 | E2F5 | E2F6 | E2F7 | E2F8 | ||||||||||
cor | P | cor | P | cor | P | cor | P | cor | P | cor | P | cor | P | cor | P | ||
| |||||||||||||||||
Monocyte | CD86 | -0.359 | ∗∗∗ | -0.328 | ∗∗∗ | -0.242 | ∗∗ | -0.140 | 0.084 | -0.261 | ∗ | -0.312 | ∗∗∗ | -0.193 | 0.016 | -0.224 | ∗ |
CD115 (CSF1R) | -0.239 | ∗ | -0.227 | ∗ | -0.097 | 0.229 | -0.006 | 0.933 | -0.349 | ∗∗∗ | -0.352 | ∗∗∗ | -0.150 | 0.062 | -0.143 | 0.076 | |
| |||||||||||||||||
TAM | CCL2 | -0.383 | ∗∗∗ | -0.415 | ∗∗∗ | -0.309 | ∗∗ | -0.111 | 0.17 | -0.203 | 0.011 | -0.228 | ∗ | -0.170 | 0.035 | -0.167 | 0.038 |
CD68 | -0.246 | ∗ | -0.210 | ∗ | -0.097 | 0.228 | 0.010 | 0.901 | -0.306 | ∗∗ | -0.380 | ∗∗∗ | -0.180 | 0.025 | -0.164 | 0.042 | |
IL10 | -0.392 | ∗∗∗ | -0.357 | ∗∗∗ | -0.289 | ∗∗ | -0.141 | 0.081 | -0.259 | ∗ | -0.398 | ∗∗∗ | -0.326 | ∗∗∗ | -0.302 | ∗∗ | |
| |||||||||||||||||
M1 macrophage | INOS (NOS2) | 0.006 | 0.936 | -0.082 | 0.308 | -0.106 | 0.19 | 0.164 | 0.042 | -0.114 | 0.159 | 0.041 | 0.61 | 0.129 | 0.11 | 0.116 | 0.153 |
IRF5 | -0.246 | ∗ | -0.262 | ∗ | -0.149 | 0.065 | 0.064 | 0.429 | -0.362 | ∗∗∗ | -0.395 | ∗∗∗ | -0.084 | 0.296 | -0.134 | 0.098 | |
COX2 (PTGS2) | -0.182 | 0.023 | -0.140 | 0.082 | 0.064 | 0.431 | 0.035 | 0.661 | -0.091 | 0.259 | -0.087 | 0.279 | -0.032 | 0.691 | 0.005 | 0.944 | |
| |||||||||||||||||
M2 macrophage | CD163 | -0.205 | 0.010 | -0.234 | ∗ | -0.126 | 0.118 | -0.070 | 0.386 | -0.192 | 0.017 | -0.243 | ∗ | -0.060 | 0.458 | -0.103 | 0.203 |
VSIG4 | -0.389 | ∗∗∗ | -0.346 | ∗∗∗ | -0.282 | ∗∗ | -0.156 | 0.052 | -0.249 | ∗ | -0.373 | ∗∗∗ | -0.276 | ∗∗ | -0.332 | ∗∗∗ | |
MS4A4A | -0.319 | ∗∗∗ | -0.295 | ∗∗ | -0.231 | ∗ | -0.173 | 0.031 | -0.253 | ∗ | -0.313 | ∗∗∗ | -0.241 | ∗ | -0.233 | ∗ | |
| |||||||||||||||||
Description | Gene markers | LGG | |||||||||||||||
E2F1 | E2F2 | E2F3 | E2F4 | E2F5 | E2F6 | E2F7 | E2F8 | ||||||||||
cor | P | cor | P | cor | P | cor | P | cor | P | cor | P | cor | P | cor | P | ||
| |||||||||||||||||
Monocyte | CD86 | -0.203 | ∗∗∗ | 0.228 | ∗∗∗ | 0.061 | 0.166 | 0.185 | ∗∗∗ | 0.004 | 0.910 | 0.074 | 0.089 | -0.004 | 0.921 | 0.157 | ∗∗ |
CD115 (CSF1R) | -0.285 | ∗∗∗ | 0.209 | ∗∗∗ | 0.048 | 0.269 | 0.114 | ∗ | -0.029 | 0.510 | -0.041 | 0.343 | -0.147 | ∗∗ | 0.055 | 0.208 | |
| |||||||||||||||||
TAM | CCL2 | -0.19 | ∗∗∗ | 0.065 | 0.137 | -0.027 | 0.532 | 0.096 | 0.028 | -0.057 | 0.188 | -0.004 | 0.922 | 0.01 | 0.818 | 0.062 | 0.153 |
CD68 | -0.124 | ∗ | 0.28 | ∗∗∗ | 0.076 | 0.084 | 0.267 | ∗∗∗ | 0.057 | 0.192 | 0.103 | 0.018 | 0.098 | 0.025 | 0.224 | ∗∗∗ | |
IL10 | -0.152 | ∗∗ | 0.183 | ∗∗∗ | 0.043 | 0.321 | 0.168 | ∗∗ | 0.002 | 0.954 | 0.035 | 0.421 | 0.049 | 0.257 | 0.145 | ∗∗ | |
| |||||||||||||||||
M1 macrophage | INOS (NOS2) | 0.197 | ∗∗∗ | -0.005 | 0.905 | 0.011 | 0.801 | 0.012 | 0.771 | -0.059 | 0.178 | 0.014 | 0.738 | 0.093 | 0.034 | 0.073 | 0.093 |
IRF5 | -0.117 | ∗ | 0.226 | ∗∗∗ | 0.008 | 0.842 | 0.285 | ∗∗∗ | -0.076 | 0.081 | 0.038 | 0.386 | 0.05 | 0.250 | 0.183 | ∗∗∗ | |
COX2 (PTGS2) | 0.009 | 0.830 | 0.008 | 0.849 | 0.077 | 0.079 | -0.038 | 0.386 | -0.109 | 0.012 | -0.072 | 0.100 | 0.047 | 0.286 | 0.051 | 0.242 | |
| |||||||||||||||||
M2 macrophage | CD163 | -0.077 | 0.077 | 0.224 | ∗∗∗ | 0.131 | ∗ | 0.193 | ∗∗∗ | 0.023 | 0.597 | 0.153 | ∗∗ | 0.142 | ∗ | 0.203 | ∗∗∗ |
VSIG4 | -0.255 | ∗∗∗ | 0.256 | ∗∗∗ | 0.098 | 0.024 | 0.183 | ∗∗∗ | 0.041 | 0.349 | 0.08 | 0.067 | -0.079 | 0.072 | 0.107 | 0.014 | |
MS4A4A | -0.157 | ∗∗ | 0.28 | ∗∗∗ | 0.134 | ∗ | 0.193 | ∗∗∗ | 0.104 | 0.017 | 0.145 | ∗∗ | 0.07 | 0.107 | 0.212 | ∗∗∗ |
Cor: R value of Spearman's correlation; TAM: tumor-associated macrophages. ∗P < 0.01; ∗∗P < 0.001; ∗∗∗P < 0.0001.