Table 4. Comparison of treatment details between SR-SNUC and SD-SNUC a .
| Variable | SR-SNUC | SD-SNUC | p -Value |
|---|---|---|---|
| Treatment lag (from diagnosis to initiation of treatment), d | |||
| Mean | 48.50 | 52.67 | 0.46 |
| Standard deviation | 31.13 | 34.72 | |
| Treatment modality | |||
| Surgery ± adjuvant chemo radiation | 06 | 02 | 0.1 |
| Neoadjuvant chemotherapy + concurrent chemoradiation | 01 | 04 | |
| Surgical approach | |||
| Endoscopic | 05 | 01 | 0.46 |
| Open | 00 | 01 | |
| Combined | 01 | 00 | |
| Oncological clearance following surgical treatment | |||
| Total clearance | 01 | 02 | 0.21 |
| Microscopic disease present | 04 | 00 | |
| Gross disease present | 01 | 00 | |
| Type of radiation therapy | |||
| VMAT | 03 | 03 | 0.46 0.23 (including UK) |
| IMRT | 03 | 00 | |
| UK | 01 | 03 | |
| Radiation dose (in cGy) | |||
| Mean | 61.56 | 66.67 | 0.43 |
| Standard deviation | 06.88 | 05.77 | |
| Interruption during radiation therapy (d) | |||
| Mean | 4.25 | 1.33 | 0.05 |
| Standard deviation | 2.50 | 0.58 | |
Abbreviations: cGy, centigray; IMRT, intensity-modulated radiation therapy; SD-SNUC, SMARCB1 -deficient sinonasal undifferentiated carcinoma; SR-SNUC, SMARCB1 -retained SNUC; UK, unknown; VMAT, volumetric modulated arc therapy.
a
excluding one case of palliative treatment in SR-SNUC which was treated with radiotherapy.