Fig. 2.

Closure times of PFA according to the presence of a platelet function disorder. PFA was conducted in a cohort of 555 consecutive patients referred with a suspected bleeding disorder. Diagnosis of platelet function disorder was achieved using light transmission aggregometry and platelet flow cytometry. We defined “confirmed platelet function disorder” as abnormal results in repeated LTA/flow cytometry measurements in the absence of other disorders and “possible platelet function disorder” with an abnormal result in one measurement available, inconclusive results or presence of concomitant disorders. LTA, light transmission aggregometry. ( A ) PFA ADP measurements, ( B ) PFA epinephrine measurements.