Table 2.
Results of laboratory examinations before and after desmopressin (DDAVP) initiation.
| Parameters | Value | Reference range | |
|---|---|---|---|
| Before DDAVP | After DDAVP | ||
| Chemistry | |||
| Aspartate aminotransferase (IU/L) | 48 | 26 | 13–30 |
| Alanine aminotransferase (IU/L) | 66 | 29 | 7–30 |
| γ-glutamyl transpeptidase (IU/L) | 29 | 29 | 9–32 |
| Blood urea nitrogen (mg/dL) | 20 | 21 | 8–21 |
| Creatinine (mg/dL) | 0.82 | 0.48 | 0.65–1.07 |
| Sodium (mmol/L) | 149 | 143 | 138–145 |
| Potassium (mmol/L) | 3.5 | 3 | 3.6–4.8 |
| Chlorine (mmol/L) | 109 | 104 | 101–108 |
| Urine osmolality (mOsm/kg•H2O) | 213 | N.A. | 50–1300 |
| Urine specific gravity | 1.006 | 1.015 | 1.006–1.030 |
| Endocrinology | |||
| Plasma renin activity (ng/mL/h) | ≤0.1 | N.A. | 0.2–2.3 |
| Active renin concentration (pg/mL) | ≤2.0 | ≤0.1 | 1.2–35.4 |
| Arginine vasopressin (pg/mL) | <0.4 | 0.5 | <2.8 |
| Plasma osmotic pressure (mOsm/kg•H2O) | 300 | 289 | 275–290 |
High plasma osmolality with low level of arginine vasopressin was noted, and the patient was diagnosed with central diabetes insipidus. DDAVP treatment increased urine osmolality and specific gravity and decreased the plasma osmotic pressure and serum sodium concentration.