Table 1.

Logarithmic sensitivity (LS) of the coefficient of variation CV of total RNAP and mature RNA fluctuations for five genes in yeast; see Sect. 2.4 for a discussion. (a) Parameter values from Supplemental Tables 2 and 4 in Zenklusen et al. (2008). The degradation rate $d_m$ of mature mRNA is estimated from the reported mean number of mature RNA, the parameters $s_u$, $s_b$, r, and Eq. (14) for the mean. (b) Logarithmic sensitivity of CV of total RNAP fluctuations. (c) Logarithmic sensitivity of CV of mature mRNA fluctuations. The most sensitive parameter and the next most sensitive one are marked in dark bold and italic, respectively

	PDR5	POL1	DOA1	MDN1	KAP104
(a)
Mean mature RNA $\#$	13.40	3.13	2.59	6.12	4.93
$⟨T⟩$(min)	4.50	3.75	2.90	16.75	3.50
$s_u$(min${}^{-1}$)	0.44	0.07	0.70	0.70	0.70
$s_b$(min${}^{-1}$)	4.70	0.68	0.12	0.12	0.12
$r$(min${}^{-1}$)	6.70	2.00	0.14	0.19	0.27
$d_m$(min${}^{-1}$)	0.04	0.06	0.05	0.03	0.05

LS	PDR5	POL1	DOA1	MDN1	KAP104
(b)
${\mathrm{\Lambda }}_{s_u}$	− 0.52	− 0.51	− 0.09	− 0.12	− 0.11
${\mathrm{\Lambda }}_{s_b}$	0.18	0.29	0.09	0.09	0.10
${\mathrm{\Lambda }}_r$	− 0.15	− 0.12	− 0.49	− 0.47	− 0.47
${\mathrm{\Lambda }}_{⟨T⟩}$	− 0.48	− 0.34	− 0.49	− 0.50	− 0.49

LS	PDR5	POL1	DOA1	MDN1	KAP104
(c)
${\mathrm{\Lambda }}_{s_u}$	− 0.50	− 0.52	− 0.09	− 0.10	− 0.11
${\mathrm{\Lambda }}_{s_b}$	0.23	0.20	0.08	0.08	0.09
${\mathrm{\Lambda }}_r$	− 0.23	− 0.15	− 0.49	− 0.48	− 0.48
${\mathrm{\Lambda }}_{d_m}$	0.50	0.47	0.50	0.50	0.50